ES

Independent Validation Papers

Coad S, et al., (2015) Validity and reliability of a novel immunoassay for Individual Profiling in Applied Sports Science. Research in Sports Medicine 23(2): 1-11.

Fisher R, et al., (2015) The validity and reliability of a salivary cortisol Point of Care Test. Journal of Athletic Enhancement 4:4-10

MacDonald L, et al., (2017) Reliability of salivary cortisol and Immunoglobulin A measurements from the IPRO before and after sprint cycling exercise. Journal of Sports Medicine and Physical Fitness. 57(12): 1680-1686

Nakamura, M. et al., (2019) Possibility of using salivary cortisol in elite soccer players for condition evaluation. Journal of High Performance Sport 4: 71-78

Mitsuishi, H. et al., (2022) The validaity of the Salivary Cortisol Analysis Method Using Cube Reader and Japanese University Students. Japanese Psychological Research. doi: 10.1111/jpr.12402

Rahilly D.O. et al., (2023) The Reliability of the Cube Reader LFD to Measure Salivary Cortisol and Salivary Immunoglobulin.  Journal of Athletic Enhancement 12:4
 

Peer-reviewed Validation papers:

Dunbar J, et al., (2015) Evaluation of a new point of care quantitative reader for salivary analysis in the English Premier League soccer environment. Brit. J Sports Med. Oct 2015.

Dunbar J, et al., (2015) Investigating the use of a Point of Care salivary Amylase Test in the English Premier League soccer environment. 8th World Congress of Science and Football, Denmark.

Dunbar J, et al., (2015) Investigating a dual sIgA and alpha amylase Point of Care test in the sporting environment. Proceedings 12th Symposium Intl Soc Ex Imunol.

Dunbar J, et al., (2013) Investigating the use of a Point of Care salivary IgG test in the sporting environment.  Proceedings 11th Symposium Intl Soc Ex Imunol.

Dunbar J, et al., (2013) Investigating the use of a Point of Care salivary cortisol test in the professional football environment. UKSCA Conference, East Midlands, UK.

Dunbar J, & Jehanli A, (2011) Investigating the use of a point of care sIgA test in English Premier League Soccer players. . Proceedings 10th Symposium Intl Soc Ex Imunol.

Jehanli A, et al., (2011) Development and validation of an oral fluid collection device and its use in the immunoassay of salivary steroids and immunoglobulins in sports persons. Proceedings 10th Symposium Intl Soc Ex Imunol

Papers using Soma technology

McGuire A, et al., (2023) Prevalence of low energy availability and associations with seasonal changes in salivary hormones and IgA in elite male Gaelic footballers. Eur J Nutr 1-2. 

Bin Eid, W. et al., (2022) Alterations in Cortisol Profiles among Mothers of Children with ASD Related to Poor Child Sleep Quality. Healthcare, 10, 666. https://doi.org/10.3390/healthcare10040666

Rossitter, A. et al., (2022) Effects of long-hail transmeridian travel on physiological, sleep, perceptual and mood markers in Olympic team support staff. Chronobiology International.  https://doi.org/10.1080/07420528.2022.2139186

Springham, M. et al., (2022) Selected Immunoendocrine Measures for Monitoring Responses to Training and Match Load in Professional Association Football: A Review of the Evidence. International Journal of Sports Physiology and Performance. https://doi.org/10.1123/ijspp.2022-0226

Mitsuishi,  H. and Ogi, T., (2022) The effects of interactive fitness video games on stress and cognitive function. Journal of Digital Life. 2(6)

Han, X. et al. (2022) Safety and Efficacy of a Multivitamin, Multimineral, Bovine Colostrum–Containing Supplement: An Open-label Pilot Intervention Trial in Healthy Adult Women. Alternative Therapies in Health and Medicine.

Morgans, R. et al., (2022) The Immunological and Hormonal Responses to Competitive Match-Play in Elite Soccer Players. International Journal of Environmental Research and Public Health. 19, 11784 https://doi.org/10.3390/ijerph191811784

Springham, M., & Dunbar, J. (2022) Match-induced Perturbations To Immunological And Hormonal Status In Elite-level Professional Football Players. Medicine and Science in Sports and Exercise 54(9S):313-314

Liang, Z. (2021) What Does Sleeping Brain Tell AboutStress? A Pilot Functional Near Infrared Spectroscopy Study Into Stress-Related Cortical Hemodynamic Features During Sleep. Frontiers in Computer Science. doi: 10.3389/fcomp.2021.774949

Rodriguez, A et al. (2021) Relationship between external load and cortisol concentrations during the competitive microcycle in international soccer players. Rev Andal Med Deporte. 14(2) Online

Rossitter, A. et al. (2021) Effect of long-haul transmeridian travel on recovery and performance in international level swimmers. International Journal of Sports Science & Coaching. DOI: 10.1177/17479541211049641

Sharp, M. et al., (2021) Marine phytoplankton improves recovery and sustains immune function in humans and lowers proinflammatory immunoregulatory cytokines in a rat model. Physical Activity and Nutrition. 25 (1): 042-055

Springham, M. et al. (2021) Summated Training and Match Load Predictors of Salivary Immunoglobulin-A, Alpha-Amylase, Testosterone, Cortisol and T:C Profile Changes in Elite-Level Professional Football Players: A Longitudinal Analysis.  European Journal of Sport Science 22 (8): 1156-1166.

Springham, M. et al. (2020) Salivary Immunoendocrine and Self-report Monitoring Profiles across an Elite-Level Professional Football Season. Medicine & Science in Sports & Exercise 53(5):p 918-927,

Tiernan C. et al., (2020) Investigation of the relationship between Salivary Cortisol, Training Load and subjective markers of recovery in elite Rugby Union players. International Journal of Sports Physiology & Performance. 15(1): 113-118. DOI: DOI: https://doi.org/10.1123/ijspp.2018-0945

Tiernan C. et al., (2020) Salivary IgA as a predictor of Upper respiratory Tract Infection and relationship to Training Load in elite Rugby Union players. Journal of Strength and Conditioning Research. 34(3): 782-790 DOI: 10.1519/JSC.0000000000003019

Rist, B. & Pearce, A. (2019) Tiered Levels of Resting Cortisol in an Athletic Population. A Potential Role for Interpretation in Biopsychosocial Assessment? Journal of. Functional. Morphology & . Kinesiology , 4, 8; doi:10.3390/jfmk4010008

Figueiredo,  P. et al., (2019) Within-Subject Correlation Between Salivary IgA and Measures of Training Load in Elite Football Players. International Journal of Sports Physiology and Performance, 14, 847-849

MacDonald L, & Minihan C, (2017) Mindfulness training attenuates the increase in salivary cortisol concentration associated with competition in highly trained wheelchair basketball players. Journal of Sports Sciences  http://dx.doi.org/10.1080/02640414.2017.1308001

Anton-Solanos A, et al., (2016) Physiological and cognitive responses to and Antarctic Expedition: A case report. International Journal of Sports Physiology and Performance. Vol 11 (8): 1053-1059.

Coad S, et al., (2016) Seasonal Analysis of Mucosal Immunological Function and Physical Demands in Professional Australian Rules Footballers. Int. J. Sports Physiol. Perf. 11(5) 574-580.

Edmonds R, et al., (2016) Cardiac  Autonomic and Salivary Responses to a Repeated Training Bout in Elite Swimmers. Sports, 4, 13, 2-14

Owen A, et al., (2016) High Intensity Training and Salivary Immunoglobuin A responses in Professional Top-Level Soccer Players. J Str. Cond. Res. 30(9): 2460-9

Dunbar J, et al., (2016) Salivary Cortisol is Highly Correlated With Training Intensity in English Premier League Players; in International Research in Science and Soccer II Eds., Favero T, et al. Routledge pp 104-109

Coad S, et al., (2015) Physical Demands and Salivary Immunoglobulin A Responses of Elite Australian Rules Football Athletes to Match Play. Int. J. Sports Physiol. Perf. 10(5) 613-617

Dimitriou L, et al., (2015) Influence of Montmorency cherry juice blend on indices of exercise-induced stress and upper respiratory tract symptoms following marathon running. J Int Soc. Sp. Nutr. 12(22)

Edmonds R, et al., (2015) Effect of chronic training on heart rate variability, salivary IgA and salivary alpha-amylase in elite swimmers with a disability. PLoS One, 10, e0127749

Morgans R, et al., (2015) Pre-Match Salivary IgA in Soccer Players From the 2014 World Cup Qualifying Campaign. International Journal of Sports Physiology and Performance 10(3): 401-403

Dunbar J, et al., (2014) Secretory IgA Responses to a Premier League Soccer Season. Proceedings of 4th World Conference of Science and Soccer, Portland, USA.

Morgans R, et al., (2014) Intensive Winter Fixture Schedule Induces a Transient Fall in Salivary IgA in English Premier League Soccer Players. Research in Sports Medicine 22: 346-354

Dunbar J, et al., (2013) Mucosal Immunity and Self-reported Upper Respiratory Symptoms in a cohort of Premier League Academy Soccer Players: Proceedings 11th Symposium Intl Soc Ex Imunol.

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REFERENCIAS PAPERS  

  1. García F, Fernández D, Vázquez-Guerrero J, et al. (2022) Recovery of the physiological status in professional basketball players using NESA neuromodulation treatment during different types of microcycles in season: A preliminary randomized clinical trial. Frontiers in Physiology. 2022;13. https://www.frontiersin.org/articles/10.3389/fphys.2022.1032020

  2. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., & Álamo-Arce, D. (2021). Nesa Non-Invasive Neuromodulation; A New Frontier of Treatment of the Autonomous Nervous System in Physiotherapy. 4.DOI: https://www.cientperiodique.com/article/CPQOS/5/4/97

  3. Teruel-Hernández, E., López-Pina, J. A., Souto-Camba, S., Báez-Suárez, A., Medina-Ramírez, R., & Gómez-Conesa, A. (2023). Improving sleep quality, daytime sleepiness, and cognitive function in patients with dementia by therapeutic exercise and NESA neuromodulation: A multicenter clinical trial. International Journal of Environmental Research and Public Health, 20(21), 7027. https://doi.org/10.3390/ijerph20217027

  4. Báez-Suárez, A., Padrón-Rodríguez, I., Castellano-Moreno, E., González-González, E., Quintana-Montesdeoca, M. P., & Medina-Ramirez, R. I. (2023). Application of non-invasive neuromodulation in children with neurodevelopmental disorders to improve their sleep quality and constipation. BMC Pediatrics, 23(1), 465. https://doi.org/10.1186/s12887-023-04307-4

  5. Contreras, M., Medina-Ramírez, R., Teruel-Hernandez, E., Vilchez-Barrera, M., Báez-Suárez, A., & Álamo Arce, David. (2023). Rehabilitation in Sleep, Pain, and Bladder Symptoms of NESA Neuromodulation Application in Multiple Sclerosis Patients: A Innovative Treatment. CPQ Medicine Journal, 15(1). https://www.cientperiodique.com/article/CPQME-15-1-439.pdf

  6. Medina-Ramírez, R., Mallol Soler, M., García, F., Pla, F., Báez-Suárez, A., Teruel Hernández, E., Álamo-Arce, D. D., & Quintana-Montesdeoca, M. d. P. (2024). Effects in sleep and recovery processes of NESA neuromodulation technique application in young professional basketball players: A preliminary study. Stresses, 4(2), 238-250. https://doi.org/10.3390/stresses4020014

  7. Bonilla-Eizaguirre, M., Martín, M., Hernández-Pérez, A., Vílchez-Barrera, M., Medina-Ramírez, R., & Báez-Suárez, A. (2024). Efficacy of NESA non-invasive neuromodulation in patients with post-traumatic cervicalgia. International Journal of Research and Scientific Innovation (IJRSI), 11(10), 474. https://doi.org/10.51244/IJRSI

  8. Vega-Delgado, N., García-Rodríguez, I., Saldanha, L., Báez-Suárez, A., Vílchez-Barrera, M., Álamo-Arce, D., Hernández-Pérez, A., & Medina-Ramírez, R. (2024). New frontier in sleep disorders: The rising of an innovative non-invasive neuromodulation treatment. International Journal of Research and Scientific Innovation (IJRSI), 11(15), 49. https://doi.org/10.51244/IJRSI.2024.11150049P 

  9. Báez-Suárez, A., Báez-Suárez, V., Saldanha, L., Vílchez-Barrera, M., Hernández-Pérez, A., & Medina-Ramírez, R. (2025). Improving Sleep Quality and Well-Being in Institutionalized Older Adults: The Potential of NESA Non-Invasive Neuromodulation Treatment. Geriatrics, 10(1), 4. https://doi.org/10.3390/geriatrics10010004 

  10. VASCULAR Front. Physiol Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial doi: 10.3389/fphys.2025.1526236 https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1526236/abstract 

  11. PAIN Azevedo, N., & Medina-Ramírez, R. (2025). Pain and the autonomic nervous system: The role of non-invasive neuromodulation with NESA microcurrents. Frontiers in Pain Research, 6, Article 1410808. https://doi.org/10.3389/fpain.2025.1410808 

 

CONGRESOS 

  1. Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce, DD. (2020). Recuperación exitosa de un Síndrome Regional Complejo a través de la electroterapia de neuromodulación del Sistema Nervioso Autónomo. 58o Congreso SERMEF. Mallorca, España. http://hdl.handle.net/10553/114084  

  2. Medina-Ramírez. (2021). ¿Los deportistas profesionales tienen una óptima calidad del sueño? Aprender a dormir, una asignatura pendiente. XXIX Reunión Anual de la Sociedad Española del Sueño, España. 

  3. Medina-Ramírez, RI., Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce. Tecnología NESA. Un nuevo tratamiento revolucionario en fisioterapia. Macaronesian Researcher`s night. In Horizonte 2020 Congress. 2020. Las Palmas, Spain.  

  4. Lledó-Amat, M., Medina-Ramírez, R., Álamo-Arce, & Arteaga-Ortiz, R. (2021). Efectos de la Neuromodulación no invasiva NESA en el tratamiento de secuelas de Ictus: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España. 

  5. Lledó-Amat, M., ancho-Francés, A., Medina-Ramírez, & Álamo-Arce, D. (2021). Tratamiento de la neuralgia del trigémino con Neuromodulación no invasiva NESA: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España. 

  6. Medina-Ramírez, R., & Roman, T. (2021). Efectos de la Neuromodulación no invasiva NESA en el tono muscular, el dolor y el sueño, en pacientes bruxistas. Aprender a dormir, una asignatura pendiente. XXI reunión Anual de la Sociedad Española del Sueño, España. 

  7. Contreras, M., & Medina-Ramírez, R. I. (2021). Caso clínico de neuromodulación superficial aplicada (NESA) en pacientes con Esclerosis Múltiple. Congreso de fisioterapia nacional UMH, España 

  8. Medina-Ramírez, R., Molina-Cedrés, F., & Moreno, A. (2022). Potenciando la fisioterapia invasiva a través del sistema nervioso autónomo. I JORNADA PRESENCIAL Fisioterapia invasiva. Barceona, Spain. 

  9. Cano-Uceda, A. Aparicio-Montero, P. Medina-ramírez, R. (2023) Effectiveness of non-invasive neuromodulation in improving sleep quality and stress in physiotherapy students. Multicenter study. In SPRM Congress 2023. Colombia. 

  10. Molina-Cedrés, F., González, M., & Medina-Ramírez, R. (2022). Combining physiotherapy techniques: Treatment of plantar fasciitis with NESA neuromodulation and electrolysis. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal. 

  11. Contreras, M., Medina-Ramírez, R., & Molina-Cedrés. (2022). Nesa Non-invasive neuromodulation; a chance to approach Sclerosis Multiple symptoms. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  12. Báez-Suárez, A., Medina-Ramírez, R., Molina-Cedrés, Padrón, I., Montesdeoca, M. del P., Castellano, E., & González, E. (2022). Can microcurrents help children with neurodevelopmental disorders with their defecation and sleep quality problems? The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  13. Ruíz-lópez, K., González, M., & Medina-Ramírez, R. (2023). NESA Neuromodulation in pelvic floor and uroginecology. I NESAevent Internacional Conference. I NESAevent Internacional Conference, Madrid, Spain. 

  14. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., Álamo Arce, D., & Mallol-Soler, M. (2022). Improving sleep quality: The new frontier of physical therapy neuromodulation of the autonomic nervous system. Congreso Internacional de Fisioterapia de Cataluña. Congreso Internacional de Fisioterapia de Cataluña, Barcelona, Spain. 

  15. Báez-Suárez, A., Pestana-Miranda,R. Álamo-Arce, D. Martín-Castillo, E., Medina-Ramírez, R.  (2020). Effectiveness of non-invasive neuromodulation in children with neurodevelopmental disorders to improve constipation and sleep quality. In SPRM Congress. Belgrade, Serbia. 

  16. Zamorano, E., & Medina-Ramírez, R. (2022). Face to Face. Neuromodulación percutánea versus no invasiva (sistemas inductivos de alta intensidad y NESA). V Congreso Internacional de Fisioterapia Invasiva. V Congreso Internacional de Fisioterapia Invasiva, Madrid, Spain. 

 

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