NESA® Medical Technology: Precision in Non-Invasive Neuromodulation

Integrate NESA® microcurrent technology into your medical practice to redefine the management of the autonomic nervous system. This innovative system is crucial for the effective treatment of chronic pain, optimization of sleep patterns, control of overactive bladder, reduction of cortisol levels, and alleviation of fatigue.

The NESA XSIGNAL® neuromodulator exemplifies clinical excellence. As a non-invasive therapeutic device, it significantly enhances patient quality of life by promoting measurable health improvements.

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experts in Non-Invasive Neuromodulation NESA®.

Innovation and precision in neuromodulation

Discover XSIGNAL®, the forefront of neuromodulation technology. This innovative medical device administers thousands of synchronized impulses per minute along optimal nerve pathways, facilitated by its advanced directional electrode. This crucial component ensures unparalleled control over the treatment process, enabling exceptional precision and adaptability.

Equipped with 24 strategically positioned electrodes, XSIGNAL® represents the culmination of over 20 years of extensive research in NESA® microcurrent technology, transforming electrical stimuli into pivotal electrophysiological breakthroughs.

We provide healthcare professionals with a tool that redefines precision and efficacy in neuromodulation, establishing a new benchmark in patient care.

Main applications
of NESA® Microcurrents

Backed by solid scientific evidence

Relieves chronic pain
and neuropathic
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Improving quality
of sleep
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Optimise recovery
of injuries
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Improves
hyperactive veijga
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Reduce stress
and anxiety
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Reduces
muscle fatigue
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How does
NESA® Non-invasive
Neuromodulation work?

NESA® redefines medical treatment with its non-invasive technology that utilizes patented smart microcurrents to positively influence the autonomic nervous system. This safe and effective approach promotes rapid and sustainable improvements in patient well-being.

NESA® achieves outstanding precision by modulating the nervous system through strategic points on the hands and feet, enhancing its integration into clinical practice without technical interruptions. It features nine clinical programs, adjustable from 1 to 15 Hertz, offering the versatility needed to address a variety of conditions and enrich both active and passive treatments without requiring a technician's presence during the session.

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NESA® Non-Invasive Neuromodulation is an effective treatment to improve ailments in which the autonomic nervous system plays a fundamental role.

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Education at the heart of NESA®

The core of NESA® is defined by our commitment to continuing education. We recognize that advancements in healthcare science, particularly in dynamic fields like non-invasive neuromodulation, begin with comprehensive and current training. Our goal is to equip healthcare professionals with the necessary tools and knowledge to effectively incorporate NESA® Non-Invasive Neuromodulation into their daily practices.

To date, over 2,500 healthcare professionals have enhanced their skills through our programs, benefiting from courses certified by the University of Las Palmas de Gran Canaria. This accomplishment highlights our dedication to educational excellence and our pivotal role in the ongoing enhancement of patient care.

Take part in our NESA® University Expert in Non-Invasive Neuromodulation, a 4-month programme with 12 experts and live webinars. This 100% online course, available in English and Spanish, equips you with advanced knowledge to treat conditions such as sports injuries and chronic pain. With two editions per year, learn through case studies and hands-on practice how to integrate NESA® technology into your practice.

Specializing in sleep from an integral perspective is achievable. 4SleepDrive® is a method developed by experts in neurology, pulmonology, neurophysiology, psychology, and physiotherapy, all specialists in sleep. This blended learning course, combining theoretical knowledge and practical application, will teach you about the neuroanatomy of sleep, its physiology, sleep pathologies, the correlation between sleep and other pathologies, assessment techniques, and non-invasive neuromodulation.

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We address a wide range of inquiries, including technical, scientific, clinical, physiological, patient-related, training, commercial, and expansion issues. Simplify your search by using keywords

Blog

NESA Life: The Movement That Transforms Lives

On our blog, you will find articles and interviews on Non-Invasive Neuromodulation of the autonomic nervous system. Explore our participation in major congresses, recent scientific studies, collaborations with universities, clinical case studies, and healthy lifestyle habits, among other topics.

Contact

At NESA WORLD®, we highly value the synergy between technological innovation and the aspirations of healthcare professionals. We recognize that each consultation is a step toward achieving excellence in healthcare.

If you are ready to discover how our solutions can contribute to your success, we encourage you to take the next step. Contact a NESA® account executive directly, who is prepared to align with your objectives and address all your inquiries.

Complete the form below to discover how your vision can be integrated with our technology to achieve exceptional results.

Start today on the path to the future of healthcare. Let us be part of your professional evolution. Contact us now.

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Join us as an official distributor! Complete our straightforward form and become part of our distribution network. As a key partner, you will promote and distribute innovative products that enhance people's quality of life.

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REFERENCES PAPERS

  1. García F, Fernández D, Vázquez-Guerrero J, et al. (2022) Recovery of the physiological status in professional basketball players using NESA neuromodulation treatment during different types of microcycles in season: A preliminary randomized clinical trial.Frontiers in Physiology. 2022;13.https://www.frontiersin.org/articles/10.3389/fphys.2022.1032020
  2. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., & Álamo-Arce, D. (2021). Nesa Non-Invasive Neuromodulation; A New Frontier of Treatment of the Autonomous Nervous System in Physiotherapy. 4.DOI: https://www.cientperiodique.com/article/CPQOS/5/4/97

  3. Teruel-Hernández, E., López-Pina, J. A., Souto-Camba, S., Báez-Suárez, A., Medina-Ramírez, R., & Gómez-Conesa, A. (2023). Improving sleep quality, daytime sleepiness, and cognitive function in patients with dementia by therapeutic exercise and NESA neuromodulation: A multicenter clinical trial. International Journal of Environmental Research and Public Health, 20(21), 7027. https://doi.org/10.3390/ijerph20217027

  4. Báez-Suárez, A., Padrón-Rodríguez, I., Castellano-Moreno, E., González-González, E., Quintana-Montesdeoca, M. P., & Medina-Ramirez, R. I. (2023). Application of non-invasive neuromodulation in children with neurodevelopmental disorders to improve their sleep quality and constipation. BMC Pediatrics, 23(1), 465. https://doi.org/10.1186/s12887-023-04307-4

  5. Contreras, M., Medina-Ramírez, R., Teruel-Hernandez, E., Vilchez-Barrera, M., Báez-Suárez, A., & Álamo Arce, David. (2023). Rehabilitation in Sleep, Pain, and Bladder Symptoms of NESA Neuromodulation Application in Multiple Sclerosis Patients: A Innovative Treatment. CPQ Medicine Journal, 15(1). https://www.cientperiodique.com/article/CPQME-15-1-439.pdf
  6. Medina-Ramírez, R., Mallol Soler, M., García, F., Pla, F., Báez-Suárez, A., Teruel Hernández, E., Álamo-Arce, D. D., & Quintana-Montesdeoca, M. d. P. (2024). Effects in sleep and recovery processes of NESA neuromodulation technique application in young professional basketball players: A preliminary study. Stresses, 4(2), 238-250. https://doi.org/10.3390/stresses4020014

  7. Bonilla-Eizaguirre, M., Martín, M., Hernández-Pérez, A., Vílchez-Barrera, M., Medina-Ramírez, R., & Báez-Suárez, A. (2024). Efficacy of NESA non-invasive neuromodulation in patients with post-traumatic cervicalgia. International Journal of Research and Scientific Innovation (IJRSI), 11(10), 474. https://doi.org/10.51244/IJRSI

  8. Vega-Delgado, N., García-Rodríguez, I., Saldanha, L., Báez-Suárez, A., Vílchez-Barrera, M., Álamo-Arce, D., Hernández-Pérez, A., & Medina-Ramírez, R. (2024). New frontier in sleep disorders: The rising of an innovative non-invasive neuromodulation treatment. International Journal of Research and Scientific Innovation (IJRSI), 11(15), 49. https://doi.org/10.51244/IJRSI.2024.11150049P

  9. Báez-Suárez, A., Báez-Suárez, V., Saldanha, L., Vílchez-Barrera, M., Hernández-Pérez, A., & Medina-Ramírez, R. (2025). Improving Sleep Quality and Well-Being in Institutionalized Older Adults: The Potential of NESA Non-Invasive Neuromodulation Treatment. Geriatrics, 10(1), 4. https://doi.org/10.3390/geriatrics10010004

  10. VASCULAR Front. Physiol Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial doi: 10.3389/fphys.2025.1526236
    https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1526236/abstract

  11. PAIN Azevedo, N., & Medina-Ramírez, R. (2025). Pain and the autonomic nervous system: The role of non-invasive neuromodulation with NESA microcurrents. Frontiers in Pain Research, 6, Article 1410808. https://doi.org/10.3389/fpain.2025.1410808

CONFERENCES

  1. Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce, DD. (2020). Recuperación exitosa de un Síndrome Regional Complejo a través de la electroterapia de neuromodulación del Sistema Nervioso Autónomo. 58o Congreso SERMEF. Mallorca, España.http://hdl.handle.net/10553/114084

  2. Medina-Ramírez. (2021). ¿Los deportistas profesionales tienen una óptima calidad del sueño?Aprender a dormir, una asignatura pendiente. XXIX Reunión Anual de la Sociedad Española del Sueño, España.

  3. Medina-Ramírez, RI., Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce. Tecnología NESA. Un nuevo tratamiento revolucionario en fisioterapia. Macaronesian Researcher`s night. In Horizonte 2020 Congress. 2020. Las Palmas, Spain.

  4. Lledó-Amat, M., Medina-Ramírez, R., Álamo-Arce, & Arteaga-Ortiz, R. (2021). Efectos de la Neuromodulación no invasiva NESA en el tratamiento de secuelas de Ictus: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España.

  5. Lledó-Amat, M., ancho-Francés, A., Medina-Ramírez, & Álamo-Arce, D. (2021). Tratamiento de la neuralgia del trigémino con Neuromodulación no invasiva NESA: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España.

  6. Medina-Ramírez, R., & Roman, T. (2021). Efectos de la Neuromodulación no invasiva NESA en el tono muscular, el dolor y el sueño, en pacientes bruxistas.Aprender a dormir, una asignatura pendiente. XXI reunión Anual de la Sociedad Española del Sueño, España.

  7. Contreras, M., & Medina-Ramírez, R. I. (2021). Caso clínico de neuromodulación superficial aplicada (NESA) en pacientes con Esclerosis Múltiple. Congreso de fisioterapia nacional UMH, España

  8. Medina-Ramírez, R., Molina-Cedrés, F., & Moreno, A. (2022). Potenciando la fisioterapia invasiva a través del sistema nervioso autónomo. I JORNADA PRESENCIAL Fisioterapia invasiva. Barceona, Spain.

  9. Cano-Uceda, A. Aparicio-Montero, P. Medina-ramírez, R. (2023) Effectiveness of non-invasive neuromodulation in improving sleep quality and stress in physiotherapy students. Multicenter study. In SPRM Congress 2023. Colombia.

  10. Molina-Cedrés, F., González, M., & Medina-Ramírez, R. (2022). Combining physiotherapy techniques: Treatment of plantar fasciitis with NESA neuromodulation and electrolysis. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  11. Contreras, M., Medina-Ramírez, R., & Molina-Cedrés. (2022). Nesa Non-invasive neuromodulation; a chance to approach Sclerosis Multiple symptoms. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  12. Báez-Suárez, A., Medina-Ramírez, R., Molina-Cedrés, Padrón, I., Montesdeoca, M. del P., Castellano, E., & González, E. (2022). Can microcurrents help children with neurodevelopmental disorders with their defecation and sleep quality problems? The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  13. Ruíz-lópez, K., González, M., & Medina-Ramírez, R. (2023). NESA Neuromodulation in pelvic floor and uroginecology. I NESAevent Internacional Conference. I NESAevent Internacional Conference, Madrid, Spain.

  14. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., Álamo Arce, D., & Mallol-Soler, M. (2022). Improving sleep quality: The new frontier of physical therapy neuromodulation of the autonomic nervous system. Congreso Internacional de Fisioterapia de Cataluña. Congreso Internacional de Fisioterapia de Cataluña, Barcelona, Spain.

  15. Báez-Suárez, A., Pestana-Miranda,R. Álamo-Arce, D. Martín-Castillo, E., Medina-Ramírez, R.(2020). Effectiveness of non-invasive neuromodulation in children with neurodevelopmental disorders to improve constipation and sleep quality. In SPRM Congress. Belgrade, Serbia.

  16. Zamorano, E., & Medina-Ramírez, R. (2022). Face to Face. Neuromodulación percutánea versus no invasiva (sistemas inductivos de alta intensidad y NESA). V Congreso Internacional de Fisioterapia Invasiva. V Congreso Internacional de Fisioterapia Invasiva, Madrid, Spain.

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