MEDICAL INNOVATION IN REHABILITATION AND TRAUMATOLOGY

Integral Recovery: Nervous and Musculoskeletal System.

Achieve faster and more sustainable results.

NESA XSIGNAL®

Our Non Invasive Neuromodulation technology acts directly on the nervous system, improving communication between the brain and the body. By regulating nerve impulses, it relieves chronic pain, accelerates muscle recovery and promotes tissue regeneration, optimizing the results of your treatments.

How can it help you?

  • Chronic pain
  • Neurological symptoms
  • Post-surgical rehabilitation

Recover better, faster and with long-lasting effects. find out how to transform the results of your treatments!

1. Chronic Pain Relief

It acts on the central nervous system to relieve acute, chronic and neuropathic pain. By regulating pain perception and promoting desensitisation of the affected areas, it optimises rehabilitation treatments and improves the patient's quality of life.

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2. Musculoskeletal Recovery

Improves vascularisation and tissue tension, accelerating functional recovery from musculoskeletal injuries. Ideal for optimising the results of rehabilitation treatments, promoting faster and more effective regeneration.

3. Improved Sleep and Well-being

It regulates the autonomic nervous system, improving the quality of sleep in REM and non-REM phases. It also contributes to pain relief in rehabilitation processes, favouring a more complete and restorative recovery.

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Global Trust in NESA®
More than 1,000 clinics, and over 50 hospitals and universities worldwide rely on our technology to optimise rehabilitation treatments and enhance patients’ quality of life.

PASSIVE NEUROMODULATION OF THE AUTONOMIC NERVOUS SYSTEM IN CLINICAL SETTINGS.

NESA® medical technology standardises passive stimulation protocols, optimising precision and multi-therapy capacity.

THERAPEUTIC SYNERGY: MANUAL TREATMENTS, EXERCISE AND NESA®.

Optimises the autonomic nervous system and boosts recovery in a single session.

Explore over 1000 testimonials from health professionals.

Do you want more information about XSIGNAL® Technology in Rehabilitation and Traumatology?

At NESA WORLD, we are available to help you. CONTACT US

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REFERENCES PAPERS

  1. García F, Fernández D, Vázquez-Guerrero J, et al. (2022) Recovery of the physiological status in professional basketball players using NESA neuromodulation treatment during different types of microcycles in season: A preliminary randomized clinical trial.Frontiers in Physiology. 2022;13.https://www.frontiersin.org/articles/10.3389/fphys.2022.1032020
  2. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., & Álamo-Arce, D. (2021). Nesa Non-Invasive Neuromodulation; A New Frontier of Treatment of the Autonomous Nervous System in Physiotherapy. 4.DOI: https://www.cientperiodique.com/article/CPQOS/5/4/97

  3. Teruel-Hernández, E., López-Pina, J. A., Souto-Camba, S., Báez-Suárez, A., Medina-Ramírez, R., & Gómez-Conesa, A. (2023). Improving sleep quality, daytime sleepiness, and cognitive function in patients with dementia by therapeutic exercise and NESA neuromodulation: A multicenter clinical trial. International Journal of Environmental Research and Public Health, 20(21), 7027. https://doi.org/10.3390/ijerph20217027

  4. Báez-Suárez, A., Padrón-Rodríguez, I., Castellano-Moreno, E., González-González, E., Quintana-Montesdeoca, M. P., & Medina-Ramirez, R. I. (2023). Application of non-invasive neuromodulation in children with neurodevelopmental disorders to improve their sleep quality and constipation. BMC Pediatrics, 23(1), 465. https://doi.org/10.1186/s12887-023-04307-4

  5. Contreras, M., Medina-Ramírez, R., Teruel-Hernandez, E., Vilchez-Barrera, M., Báez-Suárez, A., & Álamo Arce, David. (2023). Rehabilitation in Sleep, Pain, and Bladder Symptoms of NESA Neuromodulation Application in Multiple Sclerosis Patients: A Innovative Treatment. CPQ Medicine Journal, 15(1). https://www.cientperiodique.com/article/CPQME-15-1-439.pdf
  6. Medina-Ramírez, R., Mallol Soler, M., García, F., Pla, F., Báez-Suárez, A., Teruel Hernández, E., Álamo-Arce, D. D., & Quintana-Montesdeoca, M. d. P. (2024). Effects in sleep and recovery processes of NESA neuromodulation technique application in young professional basketball players: A preliminary study. Stresses, 4(2), 238-250. https://doi.org/10.3390/stresses4020014

  7. Bonilla-Eizaguirre, M., Martín, M., Hernández-Pérez, A., Vílchez-Barrera, M., Medina-Ramírez, R., & Báez-Suárez, A. (2024). Efficacy of NESA non-invasive neuromodulation in patients with post-traumatic cervicalgia. International Journal of Research and Scientific Innovation (IJRSI), 11(10), 474. https://doi.org/10.51244/IJRSI

  8. Vega-Delgado, N., García-Rodríguez, I., Saldanha, L., Báez-Suárez, A., Vílchez-Barrera, M., Álamo-Arce, D., Hernández-Pérez, A., & Medina-Ramírez, R. (2024). New frontier in sleep disorders: The rising of an innovative non-invasive neuromodulation treatment. International Journal of Research and Scientific Innovation (IJRSI), 11(15), 49. https://doi.org/10.51244/IJRSI.2024.11150049P

  9. Báez-Suárez, A., Báez-Suárez, V., Saldanha, L., Vílchez-Barrera, M., Hernández-Pérez, A., & Medina-Ramírez, R. (2025). Improving Sleep Quality and Well-Being in Institutionalized Older Adults: The Potential of NESA Non-Invasive Neuromodulation Treatment. Geriatrics, 10(1), 4. https://doi.org/10.3390/geriatrics10010004

  10. VASCULAR Front. Physiol Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial doi: 10.3389/fphys.2025.1526236
    https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1526236/abstract

  11. PAIN Azevedo, N., & Medina-Ramírez, R. (2025). Pain and the autonomic nervous system: The role of non-invasive neuromodulation with NESA microcurrents. Frontiers in Pain Research, 6, Article 1410808. https://doi.org/10.3389/fpain.2025.1410808

CONFERENCES

  1. Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce, DD. (2020). Recuperación exitosa de un Síndrome Regional Complejo a través de la electroterapia de neuromodulación del Sistema Nervioso Autónomo. 58o Congreso SERMEF. Mallorca, España.http://hdl.handle.net/10553/114084

  2. Medina-Ramírez. (2021). ¿Los deportistas profesionales tienen una óptima calidad del sueño?Aprender a dormir, una asignatura pendiente. XXIX Reunión Anual de la Sociedad Española del Sueño, España.

  3. Medina-Ramírez, RI., Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce. Tecnología NESA. Un nuevo tratamiento revolucionario en fisioterapia. Macaronesian Researcher`s night. In Horizonte 2020 Congress. 2020. Las Palmas, Spain.

  4. Lledó-Amat, M., Medina-Ramírez, R., Álamo-Arce, & Arteaga-Ortiz, R. (2021). Efectos de la Neuromodulación no invasiva NESA en el tratamiento de secuelas de Ictus: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España.

  5. Lledó-Amat, M., ancho-Francés, A., Medina-Ramírez, & Álamo-Arce, D. (2021). Tratamiento de la neuralgia del trigémino con Neuromodulación no invasiva NESA: A propósito de un caso. Congreso Nacional de Fisioterapia de la UMH, España.

  6. Medina-Ramírez, R., & Roman, T. (2021). Efectos de la Neuromodulación no invasiva NESA en el tono muscular, el dolor y el sueño, en pacientes bruxistas.Aprender a dormir, una asignatura pendiente. XXI reunión Anual de la Sociedad Española del Sueño, España.

  7. Contreras, M., & Medina-Ramírez, R. I. (2021). Caso clínico de neuromodulación superficial aplicada (NESA) en pacientes con Esclerosis Múltiple. Congreso de fisioterapia nacional UMH, España

  8. Medina-Ramírez, R., Molina-Cedrés, F., & Moreno, A. (2022). Potenciando la fisioterapia invasiva a través del sistema nervioso autónomo. I JORNADA PRESENCIAL Fisioterapia invasiva. Barceona, Spain.

  9. Cano-Uceda, A. Aparicio-Montero, P. Medina-ramírez, R. (2023) Effectiveness of non-invasive neuromodulation in improving sleep quality and stress in physiotherapy students. Multicenter study. In SPRM Congress 2023. Colombia.

  10. Molina-Cedrés, F., González, M., & Medina-Ramírez, R. (2022). Combining physiotherapy techniques: Treatment of plantar fasciitis with NESA neuromodulation and electrolysis. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  11. Contreras, M., Medina-Ramírez, R., & Molina-Cedrés. (2022). Nesa Non-invasive neuromodulation; a chance to approach Sclerosis Multiple symptoms. The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  12. Báez-Suárez, A., Medina-Ramírez, R., Molina-Cedrés, Padrón, I., Montesdeoca, M. del P., Castellano, E., & González, E. (2022). Can microcurrents help children with neurodevelopmental disorders with their defecation and sleep quality problems? The International Society for Physical Rehabilitation Medicine Conference. The International Society for Physical Rehabilitation Medicine, Lisbon, Portugal.

  13. Ruíz-lópez, K., González, M., & Medina-Ramírez, R. (2023). NESA Neuromodulation in pelvic floor and uroginecology. I NESAevent Internacional Conference. I NESAevent Internacional Conference, Madrid, Spain.

  14. Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., Álamo Arce, D., & Mallol-Soler, M. (2022). Improving sleep quality: The new frontier of physical therapy neuromodulation of the autonomic nervous system. Congreso Internacional de Fisioterapia de Cataluña. Congreso Internacional de Fisioterapia de Cataluña, Barcelona, Spain.

  15. Báez-Suárez, A., Pestana-Miranda,R. Álamo-Arce, D. Martín-Castillo, E., Medina-Ramírez, R.(2020). Effectiveness of non-invasive neuromodulation in children with neurodevelopmental disorders to improve constipation and sleep quality. In SPRM Congress. Belgrade, Serbia.

  16. Zamorano, E., & Medina-Ramírez, R. (2022). Face to Face. Neuromodulación percutánea versus no invasiva (sistemas inductivos de alta intensidad y NESA). V Congreso Internacional de Fisioterapia Invasiva. V Congreso Internacional de Fisioterapia Invasiva, Madrid, Spain.

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