This is where high technology, patient-centred design and academic rigour come together in the province of Limburg.
Nederweert, a municipality located between Eindhoven — the European epicentre of the Brainport Region — and Maastricht — home to one of the most disruptive medical universities on the continent — combines rural quality of life, a highly skilled workforce and immediate access to translational research centres.
The municipality is famous for its green cycling routes, the typical Limburg hospitality and, increasingly, for attracting health-tech companies seeking a favorable regulatory environment, multilingual talent and proximity to major logistics centers.
“Where data-driven care meets humane comfort.” – Under this philosophy, and in the scenario described above, the first NESA Clinic in the first NESA Clinic in the Netherlands.
The NESA Clinic concept
Scientific evidence
Clinical protocols designed to modulate the autonomic nervous system, based on clinical reasoning and developed by specialists from various disciplines.
Monitoring
Use of scientifically validated devices for data collection during anamnesis, development of personalized protocols and detailed analysis of results.
Experiential design
Carefully planned environment to provide comfort and encourage engagement, promoting a unique and meaningful experience.
Why does NESA® neuromodulation matter in the Netherlands?
Population Aging
The population of the Netherlands is aging at an accelerated rate: currently, the number of people living in the Netherlands is 20,8 % of citizens have 65 years of age or olderwhich represents a clear demographic change that poses new challenges for the health system and the social policies.
High Incidence of Neurological Diseases :
- The multiple sclerosis has a prevalence of 210.4 cases per 100,000 inhabitantswith a constant record of new diagnoses per year.
- The acquired brain injuries, both traumatic and non-traumaticboth traumatic and non-traumatic, have a high incidence of acquired high incidence and require continuous interventions in prevention y rehabilitation.
Sleep Disorders in the General Population: Evidence and Perspectives
- On 30,4 % of the population has short duration sleepwhile 43,2 % experience insufficient sleep.
- The deprivation of adequate restin combination with shift workis identified as the main main predictor of sleep of sleep disorders.
- The general sleep disorder (GSD) affects 32,1 % of the population, with a 34.8% prevalence in women and 29.1% in men.
- In the adolescent population, young women young women register the highest highest rates of both GSD and daytime daytime fatigue.
- There is a U-shaped relationship among the sleep schedules and sleep duration and the prevalence of GSDwhich indicates a increased risk both in rest patterns excessively short like long.
Stress, Anxiety and Depression :
- Approximately 40% of 16 to 25 year olds report experiencing report experiencing stress on a frequent basismainly associated with academic and work pressures.
- In the adult populationthe annual prevalence of the anxiety disorders reaches the 10,1 %while the mood disorders have a prevalence of 6,1 %.
Recent evidence suggests that suggest that these symptoms are associated with a dysregulation of the dysregulation of the autonomic nervous system and an alteration in the vagal responsewhich could contribute to the maintenance and aggravation of the clinical pictures.
NESA® Neuromodulation
- At restoring the functional balance of the of the autonomic nervous system, NESA® microcurrents may mitigate sympathetic mitigate the sympathetic hyperactivity associated with chronic pain and sleep sleep disorders.
- The activation of the processes of neuronal plasticity favors the regulation of sleep-wake cyclescontributing to the reduction of the prevalence of insomnia, insufficient sleep y daytime fatigue.
- By improving the brain self-regulationThis intervention promotes a decrease in the number of stress peaks and in the symptoms of anxiety y depressionoptimizing the adaptive response in the face of stressors.
- In the context of multiple sclerosis and acquired acquired brain lesions, neuromodulatoryneuromodulatory support facilitates the repair repair mechanisms y neuronal compensationcomplementing conventional treatments.
What improvements can patients achieve in these units?
- Stress reduction and exhaustion relief.
- Relief of anxious and depressive thoughts.
- Improved concentration.
- Increased sleep continuity.
- Relief of chronic pain.
- Decrease in the sensation of fatigue.
- Improved performance.
- Improved mood and increased energy.
- Reduction of rehabilitation time, among others
The mission that transforms: watch video
“Neuroplasticity is not only real, it's the rule. The brain changes as a function of use.”
– Michael Merzenich.
NESA Clinics is already in the Netherlands:
🌐 www.nesaclinics.nl
📸 @nesaclinicsnederland
References:
Centraal Bureau voor de Statistiek. (2025, January 1). Elderly people [Dashboard]. Retrieved from https://www.cbs.nl/en-gb/visualisations/dashboard-population/age/elderly-people
Kerkhof, G. A. (2017). Epidemiology of sleep and sleep disorders in The Netherlands. Sleep Medicine, 30, 229-239. https://doi.org/10.1016/j.sleep.2016.09.015
Bekkering, G. E., Bala, M. M., Reid, K., Kellen, E., Harker, J., Riemsma, R., Huygen, F. J. P. M., & Kleijnen, J. (2011). Epidemiology of chronic pain and its treatment in The Netherlands. Netherlands Journal of Medicine, 69(3), 141-153.
Zeijen, V. J. M., Kroon, A. A., van den Born, B. H., Blankestijn, P. J., Meijvis, S. C. A., Nap, A., Lipsic, E., … Daemen, J. (2023). The position of renal denervation in treatment of hypertension: An expert consensus statement. Netherlands Heart Journal, 31(1), 3-11. https://doi.org/10.1007/s12471-022-01717-4
Lemmens, C. M. C., Vanhommerig, J. W., Knottnerus, B. J., Uitdehaag, B. M. J., Mostert, J. P., & de Jong, B. A. (2025). Prevalence and incidence of multiple sclerosis in the Netherlands. Multiple Sclerosis and Related Disorders, 93, 106207. https://doi.org/10.1016/j.msard.2024.106207
Overbeek, B., van Erp, W., Eilander, H., Koopmans, R., & Lavrijsen, J. (2023, October 27). Number of people in minimally conscious state after severe brain injury established for the first time. Radboudumc News. Retrieved from https://www.radboudumc.nl/en/news-items/2023/aantal-mensen-in-minimaal-bewuste-toestand-na-ernstig-hersenletsel-voor-het-eerst-in-kaart-gebracht
National Institute for Public Health and the Environment. (2025, January 21). Persistent concerns about young adults' mental health despite slight improvement. RIVM News. Retrieved from https://www.rivm.nl/en/news/persistent-concerns-about-young-adults-mental-health-despite-slight-improvement
de Graaf, R., ten Have, M., van Gool, C. H., & van Dorsselaer, S. (2012). Prevalence of mental disorders and trends from 1996 to 2009: Results from NEMESIS-2. Tijdschrift voor Psychiatrie, 54(1), 27-38.
