{"id":64080,"date":"2025-10-31T10:47:06","date_gmt":"2025-10-31T09:47:06","guid":{"rendered":"https:\/\/nesa.world\/blog\/uncategorized-en\/can-tinnitus-be-treated-with-neuromodulation-clinical-experience-with-nesa\/"},"modified":"2025-10-31T12:09:20","modified_gmt":"2025-10-31T11:09:20","slug":"can-tinnitus-be-treated-with-neuromodulation-clinical-experience-with-nesa","status":"publish","type":"post","link":"https:\/\/nesa.world\/en\/blog\/sleep\/can-tinnitus-be-treated-with-neuromodulation-clinical-experience-with-nesa\/","title":{"rendered":"Can tinnitus be treated with neuromodulation? Clinical experience with NESA\u00ae"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"64080\" class=\"elementor elementor-64080 elementor-64033\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-403eb2da e-flex e-con-boxed e-con e-parent\" data-id=\"403eb2da\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6909424 elementor-widget elementor-widget-video\" data-id=\"6909424\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=OZA8KMk7phQ&t=3s&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-198b115a elementor-widget elementor-widget-text-editor\" data-id=\"198b115a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><span style=\"color: #ff7300;\"><b><span class=\"TextRun MacChromeBold SCXW118950805 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\">Tinnitus in figures<\/span><\/b><\/span><\/h4><p>The Apple Hearing Study (University of Michigan and Apple, 2024) reported that approximately <b>15% of more than 160,000 participants experience tinnitus daily<\/b>, and that the prevalence of daily tinnitus increases with age.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p>The study also notes that tinnitus <b>can affect sleep and concentration<\/b>, and later updates from the same research team <b>link tinnitus to mood regulation and stress<\/b>.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">These findings confirm that tinnitus is not merely an auditory symptom, but a multisystem phenomenon with broad emotional and physiological repercussions.<\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><h4><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"><br><\/span><span style=\"color: #ff7300;\"><strong><span class=\"TextRun MacChromeBold SCXW120598496 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW120598496 BCX0\">When the nervous system \u201cgoes on alert\u201d<\/span><\/span><span class=\"EOP SCXW120598496 BCX0\" data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/strong><\/span><\/h4><p><span data-contrast=\"auto\">Hearing does not function in isolation. When the autonomic nervous system (ANS) becomes <\/span>overactivated, the body enters a state of hypervigilance that can <b>amplify perception of the \u201cphantom sound\u201d<\/b> typical of tinnitus.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p>Recent studies have identified objective autonomic markers in people with severe tinnitus, including <b>increased pupil dilation<\/b>,<b> altered facial micro-expressions in response to neutral stimuli<\/b>, and a characteristic \u201cfight-or-flight\u201d response pattern. <\/p><p>This <b>autonomic imbalance<\/b> is associated with <b>heightened distress, fragmented sleep<\/b> and <b>difficulty maintaining attention<\/b>, reinforcing the connection between tinnitus, stress and ANS dysfunction.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><h4><b><span data-contrast=\"auto\"><br><span style=\"color: #ff7300;\">NESA\u00ae neuromodulation and the autonomic nervous system<\/span><\/span><\/b><span style=\"color: #ff7300;\" data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/h4><p>The NESA\u00ae XSIGNAL device delivers <b>very low-intensity biphasic microcurrents (&lt;&lt;10 \u00b5A)<\/b> via electrodes placed on the hands and feet, imperceptibly stimulating afferent and efferent fibres of the autonomic nervous system <br>Its aim is to <b>restore bioelectrical balance<\/b> and <b>promote autonomic self-regulation<\/b> through a safe, non-invasive stimulus.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p>The device holds <b>CE medical certification<\/b>, and its <b>safety has been documented in multiple clinical studies<\/b>, with no significant adverse effects reported after more than a decade of therapeutic use.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><b><span data-contrast=\"auto\">Main neurophysiological effects described:<\/span><\/b><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"multilevel\"}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b>Modulation of autonomic tone<\/b>, promoting parasympathetic predominance and reducing <b>cortisol<\/b> levels, a key biomarker of stress.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"multilevel\"}\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b>Enhancement of alpha-wave<\/b> and prefrontal activity, improving cortical noise filtering and reducing <b>central auditory gain<\/b>, mechanisms implicated in tinnitus.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"12\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"multilevel\"}\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b>Stimulation of neural plasticity<\/b>, influencing neurotransmitters such as <b>melatonin<\/b> and acetylcholine, which are central to auditory habituation and <b>restorative sleep<\/b>.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b2d5624 elementor-widget elementor-widget-image\" data-id=\"b2d5624\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"401\" src=\"https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_1.jpg\" class=\"attachment-large size-large wp-image-64043\" alt=\"\" srcset=\"https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_1.jpg 1024w, https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_1-300x150.jpg 300w, https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_1-768x385.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5ee25cc e-flex e-con-boxed e-con e-parent\" data-id=\"5ee25cc\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8569a51 elementor-widget elementor-widget-text-editor\" data-id=\"8569a51\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><span style=\"color: #ff7300;\"><b>Clinical results observed<\/b> <\/span><\/h4><p>In specialised clinical practice, the NESA\u00ae protocol is often used <b>in combination with hearing assessment, counselling, and sound-retraining or mindfulness exercises.<\/b><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">The most frequently reported outcomes include:<\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><ul><li><b>Subjective reduction<\/b> in <b>tinnitus intensity<\/b>, perceived by patients after several neuromodulation sessions.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><li><b>Reduction in tinnitus-related disability<\/b>, assessed using the Tinnitus Handicap Inventory (THI).<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><li><b>Increase in continuous sleep<\/b> time and <b>improved perceived restfulness<\/b>.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><li><b>Decrease in physiological stress markers<\/b>, such as morning <b>salivary cortisol<\/b>.<\/li><\/ul><p><br>Although these observations arise from clinical practice rather than randomised controlled trials, they are consistent with findings in other populations treated with the same technology, such as athletes, who demonstrated normalisation of cortisol profiles and improved sleep latency, with no relevant adverse effects reported.<\/p><p>\ud83d\udc49 Download the complete dossier <span style=\"text-decoration: underline;\"><a href=\"https:\/\/nesa365-my.sharepoint.com\/:f:\/g\/personal\/marketing_nesaworld_es\/EvNiDfr0kfRKtCUxYHZBd4IBhtH0WN8lPqSJ2VTwRkRA1g?e=Zf3srN\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span><\/p><h4><span style=\"color: #ff7300;\"><b><br>Mechanisms that could explain the effect<\/b> <\/span><\/h4><p>While the specific physiological mechanisms of NESA\u00ae neuromodulation in tinnitus <b>have not yet been conclusively established<\/b>, current evidence on microcurrent stimulation and autonomic regulation allows the proposal of <b>plausible hypotheses<\/b>:<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"22\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b>Autonomic balance<\/b>: possible reduction in the LF\/HF ratio of heart rate variability, together with increased cholinergic activity, which may help to dampen central auditory amplification.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"22\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b>Hormonal regulation:<\/b> observed decreases in <b>cortisol<\/b> and a potential increase in <b>melatonin<\/b> may promote <b>inhibitory plasticity<\/b> and support <b>restorative sleep<\/b>.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"22\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b>Specific plasticity:<\/b> microcurrent stimulation could induce <b>LTP\/LTD-type neural modifications<\/b> in <b>auditory and limbic networks<\/b>, facilitating tinnitus habituation and modulation of hyperactive circuits.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><p><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><h4><span style=\"color: #ff7300;\"><b>Relevance for healthcare professionals<\/b><\/span><\/h4><ul><li aria-setsize=\"-1\" data-leveltext=\"%1.\" data-font=\"Times New Roman\" data-listid=\"20\" data-list-defn-props=\"{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"1\" data-aria-level=\"1\">Provides a <b>complementary, non-pharmacological option<\/b> for cases of persistent tinnitus, particularly in patients showing signs of dysautonomia or chronic stress.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"%1.\" data-font=\"Times New Roman\" data-listid=\"20\" data-list-defn-props=\"{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"2\" data-aria-level=\"1\">Can be <b>integrated within a multidisciplinary framework<\/b>, alongside audiology, psychology, sleep medicine and neuromodulatory physiotherapy, promoting care centred on autonomic regulation and overall well-being.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><ul><li aria-setsize=\"-1\" data-leveltext=\"%1.\" data-font=\"Times New Roman\" data-listid=\"20\" data-list-defn-props=\"{\"335552541\":0,\"335559685\":720,\"335559991\":360,\"469769242\":[65533,0],\"469777803\":\"left\",\"469777804\":\"%1.\",\"469777815\":\"hybridMultilevel\"}\" data-aria-posinset=\"3\" data-aria-level=\"1\">Opens <b>new avenues for clinical research<\/b>, including the use of <b>autonomic biomarkers<\/b> (e.g. heart rate variability and cortisol) and <b>comparative studies with other neuromodulation techniques <\/b>(TMS, tDCS, etc.), <b>potentially broadening therapeutic frontiers<\/b> in otoneurology and neurorehabilitation.<span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/li><\/ul><h4><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"><br><\/span><span style=\"color: #ff7300;\"><b>Next steps and collaboration<\/b><\/span><\/h4><p><b>NESA\u00ae neuromodulation<\/b> is emerging as a <b>promising tool<\/b> in the management of tinnitus and disorders associated with autonomic dysregulation. <br><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"><br><\/span>However, its definitive validation requires multicentre controlled clinical trials, with comparative groups, longitudinal follow-up, and objective measurements of autonomic function and auditory perception. <\/p><p>Healthcare professionals and research institutions are encouraged to explore this technology, evaluate its potential across diverse clinical contexts, and participate in collaborative studies aimed at <b>consolidating the scientific evidence base<\/b> <b>and optimising neurosensory rehabilitation strategies.<\/b><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bc22b73 elementor-widget elementor-widget-image\" data-id=\"bc22b73\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"401\" src=\"https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_2.jpg\" class=\"attachment-large size-large wp-image-64053\" alt=\"\" srcset=\"https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_2.jpg 1024w, https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_2-300x150.jpg 300w, https:\/\/nesa.world\/wp-content\/uploads\/2025\/10\/1761901511373-76f76ff6-2e83-4f85-9b45-84403fb9c31b_2-768x385.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d8306fb elementor-widget elementor-widget-text-editor\" data-id=\"d8306fb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ff7300;\"><strong><span class=\"TextRun MacChromeBold SCXW154608448 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW154608448 BCX0\">Final note:<\/span><\/span><\/strong><\/span><span class=\"TextRun SCXW154608448 BCX0\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW154608448 BCX0\"> This content is for informational purposes only and does not replace individual clinical assessment or treatment. In cases of <\/span>tinnitus, referral to specialists in otoneurology or audiology is always recommended.<\/span><span class=\"EOP SCXW154608448 BCX0\" data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d52c4a1 elementor-widget elementor-widget-text-editor\" data-id=\"d52c4a1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h6><strong>References<\/strong><\/h6><p><span data-contrast=\"auto\"><span class=\"TextRun SCXW5799488 BCX0\" lang=\"NL-NL\" xml:lang=\"NL-NL\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW5799488 BCX0\">Biesinger<\/span><span class=\"NormalTextRun SCXW5799488 BCX0\">, E., Hesse, G., <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW5799488 BCX0\">Probst<\/span><span class=\"NormalTextRun SCXW5799488 BCX0\">, T., & <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW5799488 BCX0\">Sch\u00e4fer<\/span><span class=\"NormalTextRun SCXW5799488 BCX0\">, C. (2025). <\/span> <\/span><em><span class=\"TextRun SCXW5799488 BCX0\" lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW5799488 BCX0\">Retrospective chart review <\/span><span class=\"NormalTextRun SCXW5799488 BCX0\">demonstrating<\/span><span class=\"NormalTextRun SCXW5799488 BCX0\"> effectiveness of bimodal neuromodulation for tinnitus treatment<\/span><\/span><span class=\"TextRun SCXW5799488 BCX0\" lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW5799488 BCX0\">. <\/span><\/span> <\/em><strong><span class=\"TextRun MacChromeBold SCXW5799488 BCX0\" lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW5799488 BCX0\">npj<\/span><span class=\"NormalTextRun SCXW5799488 BCX0\"> Primary Care Respiratory Medicine, 35<\/span><\/span><span class=\"TextRun SCXW5799488 BCX0\" lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW5799488 BCX0\">, <\/span><\/span> <\/strong><span class=\"TextRun SCXW5799488 BCX0\" lang=\"EN-CA\" xml:lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW5799488 BCX0\">29.  <\/span><\/span><\/span><a href=\"https:\/\/doi.org\/10.1038\/s43856-025-00837-3\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1038\/s43856-025-00837-3<\/a><\/p><p><span class=\"TextRun SCXW96442083 BCX0\" lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW96442083 BCX0\">Lee, S. Y., Han, J. J., Choi, S., Lee, S., & Park, H. (2023). <\/span><\/span><em><span class=\"TextRun SCXW96442083 BCX0\" lang=\"EN-CA\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW96442083 BCX0\">Objective multidisciplinary measurements of sleep and autonomic dysfunction as risk factors for chronic subjective tinnitus. <\/span><\/span><\/em><strong><span class=\"TextRun MacChromeBold SCXW96442083 BCX0\" lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW96442083 BCX0\">Scientific<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW96442083 BCX0\">Reports<\/span><span class=\"NormalTextRun SCXW96442083 BCX0\">, 13<\/span><\/span><\/strong><span class=\"TextRun SCXW96442083 BCX0\" lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW96442083 BCX0\"><strong>, <\/strong>261. <a href=\"https:\/\/doi.org\/10.1038\/s41598-022-26450-1\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1038\/s41598-022-26450-1<\/a><\/span><\/span><\/p><p><span data-contrast=\"auto\">Lin, Y., Zhao, H., & Chen, J. (2025). <em>Objective autonomic signatures of tinnitus and sound sensitivity disorders. <\/em><\/span><b><span data-contrast=\"auto\">Science Translational Medicine, 17<\/span><\/b><span data-contrast=\"auto\">(737), eadp1934. <\/span><a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.adp1934\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1126\/scitranslmed.adp1934<\/span><\/a><span data-contrast=\"auto\"> <\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">Marks, K. L., Martel, D. T., Wu, C., Basura, G. J., Roberts, L. E., Schvartz-Leyzac, K. C., & Shore, S. E. (2022). <em>Different bimodal neuromodulation settings reduce tinnitus symptoms in a randomized clinical trial. <\/em><\/span><b><span data-contrast=\"auto\">Scientific Reports, 12<\/span><\/b><span data-contrast=\"auto\">, 10350. <\/span><a href=\"https:\/\/doi.org\/10.1038\/s41598-022-13875-x\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1038\/s41598-022-13875-x<\/span><\/a><span data-contrast=\"auto\"> <\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">Moghadam, M. H., Asadi, M., & Darvishi, E. (2025). <em>Exploring the therapeutic potential of bimodal stimulation in tinnitus: A narrative review. <\/em><\/span><b><span data-contrast=\"auto\">Annals of Medicine and Surgery, 84<\/span><\/b><span data-contrast=\"auto\">, 104887. <\/span><a href=\"https:\/\/doi.org\/10.1097\/MS9.0000000000000887\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1097\/MS9.0000000000000887<\/span><\/a><span data-contrast=\"auto\"> <\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">Probst, T., Pryss, R. C., Schlee, W., & Langguth, B. (2023). <em>The association between stress, emotional states, and tinnitus-related distress: A study of cortisol, BDNF, and hair analyses. <\/em><\/span><b><span data-contrast=\"auto\">Frontiers in Aging Neuroscience, 15<\/span><\/b><span data-contrast=\"auto\">, 1131979. <\/span><a href=\"https:\/\/doi.org\/10.3389\/fnagi.2023.1131979\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fnagi.2023.1131979<\/span><\/a><span data-contrast=\"auto\"> <\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">Yakunina, N., & Nam, E. C. (2020). <\/span><span data-contrast=\"auto\"><em>Stress and tinnitus: Transcutaneous auricular vagal nerve stimulation.<\/em> <\/span><b><span data-contrast=\"auto\">Frontiers in Psychology, 11<\/span><\/b><span data-contrast=\"auto\">, 570196. <\/span><a href=\"https:\/\/doi.org\/10.3389\/fpsyg.2020.570196\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fpsyg.2020.570196<\/span><\/a><span data-contrast=\"auto\"> <\/span><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p><p><span data-contrast=\"auto\">National Institute for Health and Care Excellence (NICE). (2020).  <\/span><i><span data-contrast=\"auto\">Tinnitus: Evidence review for neuromodulation<\/span><\/i><span data-contrast=\"auto\">. <\/span><span data-contrast=\"auto\">London: NICE. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557035?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557035<\/span><\/a><span data-ccp-props=\"{\"335551550\":6,\"335551620\":6}\"> <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>https:\/\/www.youtube.com\/watch?v=OZA8KMk7phQ&#038;t=3s Tinnitus in figures The Apple Hearing Study (University of Michigan and Apple, 2024) reported that approximately 15% of more than 160,000 participants experience tinnitus daily, and that the prevalence [&hellip;]<\/p>\n","protected":false},"author":128,"featured_media":64066,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[394,330,331,353,335,315,393],"tags":[395,396],"class_list":["post-64080","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anxiety","category-depression","category-nesa-microcurrents","category-non-invasive-neuromodulation","category-pain","category-sleep","category-stress","tag-disfunciones-neurologicas-y-disautonomias","tag-sleep"],"acf":[],"_links":{"self":[{"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/posts\/64080","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/users\/128"}],"replies":[{"embeddable":true,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/comments?post=64080"}],"version-history":[{"count":0,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/posts\/64080\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/media\/64066"}],"wp:attachment":[{"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/media?parent=64080"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/categories?post=64080"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nesa.world\/en\/wp-json\/wp\/v2\/tags?post=64080"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}