In this section you will find all the works completed by the national and international research team of non-invasive neuromodulation of topological application NESA®.
Keywords: neuromodulation; Non-invasive neuromodulation; Microcurrents; Autonomous Nerve System; ANDelectrotherapy; Physiotherapy Modalities
published studies
Rico, P., & Aranguren, P. (2016). Superficial neurostimulation application, alpha rhythm and clinical effects. European Psychiatry, 33, S232. https://doi.org/10.1016/j.eurpsy.2016.01.578
Molina, F., Medina-Ramírez, R., Báez, A. Álamo-Arce, DD. 2020. Successful recovery from a Complex Regional Syndrome through neuromodulation electrotherapy of the Autonomous Nervous System. In J. Chaler Vilasecade of the president of the congress. 58th SERMEF Congress. Majorca, Spain.
Báez-Suárez, A., Pestana-Miranda, R. Álamo-Arce, D. Martín-Castillo, E., Medina-Ramírez, R. 2020. Effectiveness of non-invasive neuromodulation in children with neurodevelopmental disorders to improve constipation and sleep quality. In SPRM Congress 2020. Belgrade, Serbia.
Medina-Ramirez, RI., Molina, F., Medina-Ramirez, R., Baez, A. Alamo-Arce. NESA technology. A revolutionary new treatment in physiotherapy. Macaronesian Researcher`s night. In Horizon 2020 Congress. 2020. Las Palmas, Spain.
Lledó-Amat, M., ancho-Francés, A., Medina-Ramírez, & Álamo-Arce, D. (2021). Treatment of trigeminal neuralgia with non-invasive NESA Neuromodulation: About a case. National Congress of Physiotherapy of the UMH, Spain.
Lledó-Amat, M., Medina-Ramírez, R., Álamo-Arce, & Arteaga-Ortiz, R. (2021). Effects of non-invasive NESA Neuromodulation in the treatment of stroke sequelae: About a case. National Congress of Physiotherapy of the UMH, Spain.
Contreras, M., & Medina-Ramirez, RI (2021). Clinical case of applied superficial neuromodulation (NESA) in patients with Multiple Sclerosis. National Physiotherapy Congress UMH, Spain.
Medina-Ramírez, R., Molina-Cedrés, F., Báez-Suárez, A., & Álamo-Arce, D. (2021). Nesa Noninvasive Neuromodulation; A New Frontier of Treatment of the Autonomous Nervous System in Physiotherapy. 4. https://www.cientperiodique.com/article/CPQOS/5/4/97
Last update 12/2021.
Internal research work carried out and not published:
1st “Efficacy of treatment with NESA Xsignal® electrostimulator in patients with post-traumatic neck pain” Institution: Servicio de Rehabilitación ACTIVA Mutua Madrid Barcelona-Córdoba.
Summary: 21 patients with the diagnosis of whiplash (classification of grade I-II cervical injury, following the Foreman and Croft Classification). Said evaluation has been carried out with the biomechanical analysis system “Biomek” (Movement analysis is performed using three-dimensional videophotogrammetry - motion capture
using several infrared light-emitting cameras) at the start of protocolized rehabilitation treatment and after 14 days. The physiotherapy protocol consists of the application of an electrostimulator (NESA XSIGNAL®) combined with exercise active for 14 days in patients diagnosed with post-traumatic neck pain as a result of a traffic accident roam. Neck pain and disability questionnaires were also administered at the beginning and after 14 days.
Results: Good correlation between the reduction of cervical mobility restriction and the manifestation of pain and disability in 14 days. Statistically analyzed the mobility data (initial assessment vs. evolutionary control) there is evidence of a significant increase in mobility in the 4 movements: flexion, extension, lateral flexion and rotation. In relation to the values of the questionnaires, a decrease in pain and cervical disability was obtained. with respect to the initial values.
Conclusions: In our study, the usefulness of the biomechanical test to determine the degree of cervical involvement and monitor the rehabilitation treatment in order to establish the protocols and apply the novel physical procedures.
2º “Qualitative study of effectiveness, safety and Functioning of the NESA xsignal device”. Institution: Hospital Quiron Sevilla.
Summary: 10 patients with relative homogeneity in symptoms were evaluated, as well as as anthropometric variables. Clinical results were recorded in all cases. relevant to pain relief. In most of the recorded cases, said improvement was reported before the fifth intervention session with the NXsignal device ®.
3º “Evaluation of the impact on cognitive performance and response parameters inflammation in relation to high intensity exercise in athletes with a high level of training (CrossFit ®) by the application of superficial neurostimulation”. Institution: Sant Cugat High Performance Center.
Summary: Pilot study in which athletes are intervened for 3 months CrossFit ® practitioners. In the first phase, a work session is established resistance force standard. The initial sample was 20 individuals of age (21-35 years), who underwent a medical examination, with blood analysis and test of maximum effort, to rule out inflammatory pathology, discriminate the risk cardiovascular and characterize level of aerobic physical condition. After the first 30 minutes of training, a new blood extraction was carried out, which will be repeated at 2 hours and 30 minutes after the end of the exercise.
On the other hand, after finishing the treatment with NESA Xsignal® (90 minutes post training), the battery of neurocognitive tests that were developed during the first medical visit and, in relation to strength tests, 10 minutes after Once the exercise was finished, fatigue tests were carried out, similar to the previous phase of training since 2 hours and 10 minutes (after blood extraction and post intervention with NESA Xsignal®).
Results:
– The sample was homogeneous.
– There is a tendency to better recover the group with NESA Xsignal®, which in turn loses less speed in the immediate post-exercise.
– The group intervened with the device showed less presence of response inflammatory (cytokine level).
– Both groups improved neurocognitive response. The NESA Xsignal® Group presented a tendency to improve the correct answers in the tests.
4º «Comparative study of the frontal EGG activity after superficial neuro-stimulation application, mindfulness and other attentional techniques.» YoInstitution: University of Alcalá de Henares.
Subsequently, the same authors designed a study with onektivop, with the aim of to compare the electrical changes observed after the use of neuromodulation did not NESA with other mental concentration techniques: Mindfulness (mental attention without judgment) and a technique based on the emission of a sound. application was used
NESA microcurrents and was evaluated through digital Encephalogram; Faraday cage.
Results Mindfulness and SNSA techniques show similarities with respect to the frequency of the alpha rhythm in the frontal regions (Figures 1 and 2) compared to a technology of different mental concentration nique (figure 3). However, they need scalable studies to determine more generalizable results.
5th “Effectiveness of NESA non-invasive neuromodulation in quality improvement of sleep and well-being in soccer players; viability study"
Institution: Alfonso X el Sabio University, Madrid. Spain
Objective: Verify the effectiveness of the application of non-invasive neuromodulation NESA on improving the quality of sleep and well-being of soccer players in a professional team.
o Determine improvement in sleep quality
o Assess changes in cortisol concentrations related to sleep and stress. o Check the feasibility of the study for a subsequent clinical trial
Type of study: Final Degree Project. Prospective feasibility study of intervention in two groups of professional soccer athletes (intervention and placebo).
Subjects: Healthy soccer players without previous injuries.
Intervention: 10 sessions, 2 times a week. Applying a core protocol combining P1, P7, P5. Q4 and Q8.
Results: After analyzing the results, a significant difference was obtained for the improvement of sleep quality (pvalue= 0.041) post intervention in the experimental group. Y although no differences were obtained for cortisol levels, a significant Pearson correlation (pvalue= 0.009) between the decrease in cortisol post treatment and improvement of sleep quality.
